Investigators have discovered new mechanisms underlying intratumor heterogeneity and treatment resistance in meningiomas, the most common type of primary central nervous system tumor, according to a recent study published in Nature Genetics.
Browsing: Disease Discoveries
A recent study from the laboratory of Shi-Yuan Cheng, PhD, has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in The Journal of Clinical Investigation.
A unique genetic variation in the MAPT gene was associated with increased risk of Pick’s disease, a rare form of frontotemporal dementia, according to a recent study published in The Lancet Neurology.
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center of Northwestern University’s Prostate Cancer SPORE.
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation that can lead to rejection, according to a study published in the Journal of Clinical Investigation.
A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson’s disease, findings that demonstrate the potential for using DNA methylation as a biomarker to identify the disease.
Recent studies from Feinberg scientists have uncovered new insights into these disorders, elucidating the mechanisms behind Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis, or ALS.
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer cells may decrease cancer cell differentiation and tumor growth, according to findings published in Nature Communications.
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature Communications.